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LBS-008
Ueda, K. et al. (2016)
Photodegradation of Retinal Bisretinoids in Mouse Models and Implications for Macular Degeneration. Proceedings of the National Academy of Sciences of the United States of America
113(25): 6904–6909
Petrukhin, K. (2013)
Pharmacological Inhibition of Lipofuscin Accumulation in the Retina as a Therapeutic Strategy for Dry AMD Treatment. Drug discovery today. Therapeutic strategies
10(1): e11–20
Kim, S. R. et al. (2007)
The All-Trans-Retinal Dimer Series of Lipofuscin Pigments in Retinal Pigment Epithelial Cells in a Recessive Stargardt Disease Model. Proceedings of the National Academy of Sciences
104(49): 19273–19278
Radu, R. A. et al. (2003)
Treatment with Isotretinoin Inhibits Lipofuscin Accumulation in a Mouse Model of Recessive Stargardt’s Macular Degeneration. Proceedings of the National Academy of Sciences
100(8): 4742–4747
Sparrow, J. R. et al. (2003)
A2E, a Byproduct of the Visual Cycle. Vision research
43(28): 2983–2990
LBS-007
Huggett, M. T. et al. (2016)
Cdc7 Is a Potent Anti-Cancer Target in Pancreatic Cancer due to Abrogation of the DNA Origin Activation Checkpoint. Oncotarget
7(14): 18495–18507
Montagnoli, A. et al. (2010)
Targeting Cell Division Cycle 7 Kinase: A New Approach for Cancer Therapy. Clinical Cancer Research
16(18): 4503–4508
LBS-002
Gurgis, F. M. S et al. (2015)
Cytotoxic Activity of the MK2 Inhibitor CMPD1 in Glioblastoma Cells Is Independent of MK2. Cell Death Discovery
1: 15028
Mukhtar, E. et al. (2014)
Targeting Microtubules by Natural Agents for Cancer Therapy. Molecular cancer therapeutics
13(2): 275–284
Yuan, J. et al. (2010)
MAPK-Activated Protein Kinase 2 Is Required for Mouse Meiotic Spindle Assembly and Kinetochore-Microtubule Attachment. PLoS ONE
5(6): e11247